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Titel:

tRNAGlyGCC-Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression.

Dokumenttyp:
Journal Article
Autor(en):
Panoutsopoulou, Konstantina; Dreyer, Tobias; Dorn, Julia; Obermayr, Eva; Mahner, Sven; Gorp, Toon van; Braicu, Ioana; Zeillinger, Robert; Magdolen, Viktor; Avgeris, Margaritis; Scorilas, Andreas
Abstract:
Epithelial ovarian cancer (EOC) remains a highly-lethal gynecological malignancy, characterized by frequent recurrence, chemotherapy resistance and poor 5-year survival. Identifying novel predictive molecular markers remains an overdue challenge in the disease's clinical management. Herein, in silico analysis of TCGA-OV highlighted the tRNA-derived internal fragment (i-tRF-GlyGCC) among the most abundant tRFs in ovarian tumors, while target prediction and gene ontology (GO) enrichment analysis p...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2021
Band / Volume:
14
Heft / Issue:
1
Volltext / DOI:
doi:10.3390/cancers14010024
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35008188
TUM Einrichtung:
Klinik und Poliklinik für Frauenheilkunde
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