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Titel:

Non-collagenous extracellular matrix protein dermatopontin may play a role as another component of transforming growth factor-β signaling pathway in colon carcinogenesis.

Dokumenttyp:
Journal Article
Autor(en):
Sadr-Nabavi, Ariane; Bouromand-Noughabi, Samaneh; Tayebi-Meybodi, Naser; Dadkhah, Kimia; Amini, Nafiseh; Meindl, Alfons; Abbaszadegan, Mohammad Reza
Abstract:
OBJECTIVES: Dermatopontin (DPT) is an extracellular matrix protein that plays roles in increasing the activity of transforming growth factor-β (TGF-β) and induction of cell quiescence. These roles suggest a tumor suppressor function for DPT. This study aimed to investigate changes in DPT gene expression in colorectal cancer providing a better understanding of its carcinogenesis. MATERIALS AND METHODS: We used Matched Tumor/Normal Expression Array and Cancer Profiling Arrays I containing 34 and 7...     »
Zeitschriftentitel:
Majallah-iulum-i payah-i pizishki-i Iran = Iranian journal of basic medical sci
Jahr:
2021
Band / Volume:
24
Heft / Issue:
4
Seitenangaben Beitrag:
444-450
Volltext / DOI:
doi:10.22038/IJBMS.2021.46422.10720
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34094025
Print-ISSN:
2008-3866
TUM Einrichtung:
597; Frauenklinik und Poliklinik
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