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Titel:

IL-4 mRNA Is Downregulated in the Liver of Pancreatic Cancer Patients Suffering from Cachexia.

Dokumenttyp:
Journal Article; Article
Autor(en):
Prokopchuk, Olga; Steinacker, Jürgen M; Nitsche, Ulrich; Otto, Stephanie; Bachmann, Jeannine; Schubert, Elaine C; Friess, Helmut; Martignoni, Marc E
Abstract:
Interleukin-4 (IL-4) together with interleukin-13 (IL-13) play an important role in inflammation and wound repair, and are known to be upregulated in human skeletal muscle after strenuous physical exercise. Additionally, these cytokines may act as autocrine growth factors in pancreatic cancer cells. We hypothesize that IL-4, IL-13, and their corresponding receptors are involved in mechanism of cancer cachexia.Tissue samples from human skeletal muscle, white fat, liver, healthy pancreas, and panc...     »
Zeitschriftentitel:
Nutr Cancer
Jahr:
2017
Band / Volume:
69
Heft / Issue:
1
Seitenangaben Beitrag:
84-91
Sprache:
eng
Volltext / DOI:
doi:10.1080/01635581.2017.1247885
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27897439
Print-ISSN:
0163-5581
TUM Einrichtung:
Chirurgische Klinik und Poliklinik
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