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Title:

Novel prognostic histopathological grading system in oral squamous cell carcinoma based on tumour budding and cell nest size shows high interobserver and intraobserver concordance.

Document type:
Evaluation Studies; Journal Article
Author(s):
Boxberg, Melanie; Bollwein, Christine; Jöhrens, Korinna; Kuhn, Peer-Hendrik; Haller, Bernhard; Steiger, Katja; Wolff, Klaus-Dietrich; Kolk, Andreas; Jesinghaus, Moritz; Weichert, Wilko
Abstract:
AIMS: Squamous cell carcinoma of the oral cavity (OSCC) is a common tumour entity with a variable, partially highly aggressive clinical course. Recently, we proposed a novel (three-tiered) clinically useful grading scheme strongly associated with patient outcome in OSCC, consisting of a sum score of the histomorphological patterns tumour budding and cell nest size which outperforms WHO based grading algorithms currently in use. The aim of our study was to probe for interobserver and intraobserve...     »
Journal title abbreviation:
J Clin Pathol
Year:
2019
Journal volume:
72
Journal issue:
4
Pages contribution:
285-294
Language:
eng
Fulltext / DOI:
doi:10.1136/jclinpath-2018-205454
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30530818
Print-ISSN:
0021-9746
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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