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Titel:

Biodegradable fluorescent nanoparticles for endoscopic detection of colorectal carcinogenesis.

Dokumenttyp:
Article
Autor(en):
Rogalla, Stephan; Flisikowski, Krzysztof; Gorpas, Dimitris; Mayer, Aaron T.; Flisikowska, Tatiana; Mandella, Michael J.; Ma, Xiaopeng; Casey, Kerriann M.; Felt, Stephen A.; Saur, Dieter; Ntziachristos, Vasilis; Schnieke, Angelika; Contag, Christopher H.; Gambhir, Sanjiv S.; Harmsen, Stefan
Abstract:
Early and comprehensive endoscopic detection of colonic dysplasia - the most clinically significant precursor lesion to colorectal adenocarcinoma - provides an opportunity for timely, minimally-invasive intervention to prevent malignant transformation. Here, the development and evaluation of biodegradable near-infrared fluorescent silica nanoparticles (FSN) is described that have the potential to improve adenoma detection during fluorescence-assisted white-light colonoscopic surveillance in rode...     »
Zeitschriftentitel:
Adv. Funct. Mater.
Jahr:
2019
Band / Volume:
29
Heft / Issue:
51
Volltext / DOI:
doi:10.1002/adfm.201904992
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33041743
Print-ISSN:
1616-301X
TUM Einrichtung:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos); Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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