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Title:

NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB.

Document type:
Journal Article; Review
Author(s):
Kabacaoglu, Derya; Ruess, Dietrich A; Ai, Jiaoyu; Algül, Hana
Abstract:
Regulation of Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)/Rel transcription factors (TFs) is extremely cell-type-specific owing to their ability to act disparately in the context of cellular homeostasis driven by cellular fate and the microenvironment. This is also valid for tumor cells in which every single component shows heterogenic effects. Whereas many studies highlighted a per se oncogenic function for NF-κB/Rel TFs across cancers, recent advances in the field re...     »
Journal title abbreviation:
Cancers
Year:
2019
Journal volume:
11
Journal issue:
7
Fulltext / DOI:
doi:10.3390/cancers11070937
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31277415
Print-ISSN:
2072-6694
TUM Institution:
Lehrstuhl für Tumormetabolismus (Prof. Algül)
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