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Document type:
Journal Article
Author(s):
Kwak, Mingyu; Ninche, Ninche; Klein, Sabine; Saur, Dieter; Ghazizadeh, Soosan
Title:
c-Kit+ Cells in Adult Salivary Glands do not Function as Tissue Stem Cells.
Abstract:
A rare population of salivary gland cells isolated based on c-Kit immunoreactivity are thought to represent tissue stem cells since they exhibit the most robust proliferative and differentiation capacity ex vivo. Despite their high promise for cell-based therapies aimed at restoring salivary function, the precise location and in vivo function of c-Kit+ stem cells remain unclear. Here, by combining immunostaining with c-KitCreERT2-based genetic labeling and lineage tracing in the adult mouse sali...     »
Journal title abbreviation:
Sci Rep
Year:
2018
Journal volume:
8
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s41598-018-32557-1
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30242278
Print-ISSN:
2045-2322
TUM Institution:
Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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