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Title:

Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.

Document type:
Journal Article
Author(s):
Jesinghaus, Moritz; Konukiewitz, Björn; Foersch, Sebastian; Stenzinger, Albrecht; Steiger, Katja; Muckenhuber, Alexander; Groß, Claudia; Mollenhauer, Martin; Roth, Wilfried; Detlefsen, Sönke; Weichert, Wilko; Klöppel, Günter; Pfarr, Nicole; Schlitter, Anna Melissa
Abstract:
The appendix gives rise to goblet cell carcinoids, which represent special carcinomas with distinct biological and histological features. Their genetic background and molecular relationship to colorectal adenocarcinoma is largely unknown. We therefore performed a next-generation sequencing analysis of 25 appendiceal carcinomas including 11 goblet cell carcinoids, 7 adenocarcinomas ex-goblet cell carcinoid, and 7 primary colorectal-type adenocarcinomas, using a modified Colorectal Cancer specific...     »
Journal title abbreviation:
Mod Pathol
Year:
2018
Journal volume:
31
Journal issue:
5
Pages contribution:
829-839
Language:
eng
Fulltext / DOI:
doi:10.1038/modpathol.2017.184
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29327707
Print-ISSN:
0893-3952
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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