Predicted clinical factors associated with the intensive care unit length of stay after total cavopulmonary connection.

Ono, Masamichi; Burri, Melchior; Balling, Gunter; Beran, Elisabeth; Cleuziou, Julie; Pabst von Ohain, Jelena; Strbad, Martina; Hager, Alfred; Hörer, Jürgen; Lange, Rüdiger

doi:10.1016/j.jtcvs.2018.10.144

journal article

Titel:: Predicted clinical factors associated with the intensive care unit length of stay after total cavopulmonary connection.
Dokumenttyp:: Journal Article
Autor(en):: Ono, Masamichi; Burri, Melchior; Balling, Gunter; Beran, Elisabeth; Cleuziou, Julie; Pabst von Ohain, Jelena; Strbad, Martina; Hager, Alfred; Hörer, Jürgen; Lange, Rüdiger
Abstract:: OBJECTIVES: A longer length of stay (LOS) in the intensive care unit (ICU) after the total cavopulmonary connection (TCPC) is thought to be a predictive sign of late Fontan failure. This study was performed to determine the clinical risk factors for ICU LOS. METHODS: In total, 483 patients who underwent a TCPC between May 1994 and December 2016 were included the study. Patients' main diagnosis, morphologic characteristics, palliative procedures, hemodynamic parameters, and perioperative variables, were analyzed to identify risk factors influencing ICU stay based on Cox regression. Causes of longer ICU LOS and the impact of ICU LOS on late outcomes were evaluated. RESULTS: Age at TCPC, type of TCPC, and fenestration at TCPC did not affect the ICU LOS. With multivariable model, hypoplastic left heart syndrome (P = .001) and anomalous systemic venous drainage (P < .001) were identified as independent morphologic risk factors for prolonged ICU LOS. Of hemodynamic variables, preoperative high transpulmonary gradient (P = .037), and low aortic oxygen saturation (P = .031) were risks for longer ICU LOS. Of postoperative variables, pleural effusion (P < .001), chylothorax (P = .001), ascites (P < .001), and infection (P = .028) were risks for longer ICU LOS. The ICU LOS was found to be significantly associated with late mortality (P < .001) and late cardiac reoperation (P = .007). CONCLUSIONS: Patients with hypoplastic left heart syndrome and anomalous systemic venous drainage had longer ICU LOS. Extended cyanosis and elevated pulmonary artery pressure affect the ICU LOS. Special care should be provided during the initial postoperative phase in patients with such risk factors.
Zeitschriftentitel:: J Thorac Cardiovasc Surg
Jahr:: 2019
Band / Volume:: 157
Heft / Issue:: 5
Seitenangaben Beitrag:: 2005-2013.e3
Volltext / DOI:: doi:10.1016/j.jtcvs.2018.10.144
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/30578061
Print-ISSN:: 0022-5223
TUM Einrichtung:: Klinik für Herz- und Gefäßchirurgie (Prof. Lange); Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum Klinik für Kinderkardiologie und angeborene Herzfehler (DHM) (Prof. Ewert)2019

mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum Klinik für Herz- und Gefäßchirurgie (DHM) (Prof. Krane)2019