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- Document type:
- Journal Article; Editorial Material
- Author(s):
- Tschöp, Matthias H; Stumvoll, Michael; Ristow, Michael
- Title:
- Opposing Effects of Antidiabetic Interventions on Malignant Growth and Metastasis.
- Abstract:
- Type 2 diabetes is associated with increased risk of malignancies, whereas antidiabetic interventions like physical exercise or metformin reduce cancer incidence. A recent publication shows that one diabetes treatment approach, namely incretin-related DPP4 inhibitors, increases metastatic capacity by activating the antioxidant transcription factor NRF2 to decrease reactive oxygen species (ROS) levels.
- Journal title abbreviation:
- Cell Metab
- Year:
- 2016
- Journal volume:
- 23
- Journal issue:
- 6
- Pages contribution:
- 959-60
- Fulltext / DOI:
- doi:10.1016/j.cmet.2016.05.017
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/27304493
- Print-ISSN:
- 1550-4131
- TUM Institution:
- Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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