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Title:

Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Hilvo, Mika; Meikle, Peter J; Pedersen, Eva Ringdal; Tell, Grethe S; Dhar, Indu; Brenner, Hermann; Schöttker, Ben; Lääperi, Mitja; Kauhanen, Dimple; Koistinen, Kaisa M; Jylhä, Antti; Huynh, Kevin; Mellett, Natalie A; Tonkin, Andrew M; Sullivan, David R; Simes, John; Nestel, Paul; Koenig, Wolfgang; Rothenbacher, Dietrich; Nygård, Ottar; Laaksonen, Reijo
Abstract:
AIMS: Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease (CVD) events, especially cardiovascular death. As phospholipids have also been linked with CVD risk, we investigated whether the combination of ceramides with phosphatidylcholines (PCs) would be synergistic in the prediction of CVD events in patients with atherosclerotic coronary heart disease in three independent cohort studies. METHODS AND RESULTS: Ceramides and PCs were analysed using liquid chromato...     »
Journal title abbreviation:
Eur Heart J
Year:
2020
Journal volume:
41
Journal issue:
3
Pages contribution:
371-380
Fulltext / DOI:
doi:10.1093/eurheartj/ehz387
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31209498
Print-ISSN:
0195-668X
TUM Institution:
273; Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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