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Titel:

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps.

Dokumenttyp:
Article; Journal Article
Autor(en):
Marx, Charlotte; Novotny, Julia; Salbeck, Danby; Zellner, Katie R; Nicolai, Leo; Pekayvaz, Kami; Kilani, Badr; Stockhausen, Sven; Bürgener, Niklas; Kupka, Danny; Stocker, Thomas J; Weckbach, Ludwig T; Pircher, Joachim; Moser, Markus; Joner, Michael; Desmet, Walter; Adriaenssens, Tom; Neumann, Franz-Josef; Gerschlick, Anthony H; Ten Berg, Jurrien M; Lorenz, Michael; Stark, Konstantin
Abstract:
Clinical observations implicate a role of eosinophils in cardiovascular diseases because markers of eosinophil activation are elevated in atherosclerosis and thrombosis. However, their contribution to atherosclerotic plaque formation and arterial thrombosis remains unclear. In these settings, we investigated how eosinophils are recruited and activated through an interplay with platelets. Here, we provide evidence for a central importance of eosinophil-platelet interactions in atherosclerosis and...     »
Zeitschriftentitel:
Blood
Jahr:
2019
Band / Volume:
134
Heft / Issue:
21
Seitenangaben Beitrag:
1859-1872
Volltext / DOI:
doi:10.1182/blood.2019000518
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31481482
Print-ISSN:
0006-4971
TUM Einrichtung:
Experimentelle Hämatologie (Prof. Schmidt-Supprian); Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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