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Title:

Prognostic value of kallikrein-related peptidase 12 (KLK12) mRNA expression in triple-negative breast cancer patients.

Document type:
Journal Article
Author(s):
Gong, Weiwei; Liu, Yueyang; Preis, Sarah; Geng, Xiaocong; Petit-Courty, Agnes; Kiechle, Marion; Muckenhuber, Alexander; Dreyer, Tobias; Dorn, Julia; Courty, Yves; Magdolen, Viktor
Abstract:
BACKGROUND: The serine protease KLK12 belongs to the human fifteen-member family of kallikrein-related peptidases. Differential expression accompanied by either increased or decreased enzymatic activity has been linked to several diseases including cancer. Triple-negative breast cancer (TNBC) represents a very aggressive subgroup of breast cancer with high tumor recurrence rates and poor patient prognosis. Here, we quantified the KLK12 mRNA expression levels in tumor tissue of TNBC patients and...     »
Journal title abbreviation:
Mol Med
Year:
2020
Journal volume:
26
Journal issue:
1
Fulltext / DOI:
doi:10.1186/s10020-020-0145-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32028882
Print-ISSN:
1076-1551
TUM Institution:
Frauenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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