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- Dokumenttyp:
- Article; Journal Article; Research Support, Non-U.S. Gov't
- Autor(en):
- Thill, Marc; Faridi, Andree; Meiré, Anette; Gerber-Schäfer, Claudia; Baumann, Kristin; Blohmer, Jens-Uwe; Mau, Christine; Tofall, Sabrina; Nolte, Elke; Strittmatter, Hans-Joachim; Ohlinger, Ralf; Paepke, Stefan
- Titel:
- Patient reported outcome and cosmetic evaluation following implant-based breast-reconstruction with a titanized polypropylene mesh (TiLOOP® Bra): A prospective clinical study in 269 patients.
- Abstract:
- INTRODUCTION: Implant-based or expander-supported breast reconstruction is an established surgical method after mastectomies due to cancer or to prophylactic reasons. Patient reported outcome (PRO) and cosmetic outcome after breast reconstruction with a synthetic surgical mesh was investigated in a prospective, single-arm, multi-center study. MATERIAL AND METHODS: Primary or secondary implant-based breast reconstruction with support of TiLOOP® Bra was performed in 269 patients during the PRO-BRA study. PRO 12 months after breast reconstruction was evaluated using Breast-Q questionnaire. Cosmetic outcome was evaluated by two independent experts by means of pictures taken preoperatively and at the follow-up visits. RESULTS: Breast-Q and 12 months FU were completed by 210 women. Patients without adverse event had a significantly higher Breast-Q score for "sexual well-being" (p = 0.001); "psychosocial well-being" was negatively influenced by prior therapies (p < 0.01), and older patients had significantly lower scores at 12 months FU compared to pre-OP for "satisfaction with breasts" (p < 0.01) while the opposite was true for younger patients. Unilateral surgery resulted in reduced "satisfaction with breast" at 12 months FU (p < 0.01). Radiotherapy negatively influenced "satisfaction with breast", "sexual well-being" and "physical well-being chest". The cosmetic evaluation showed a significant difference (p < 0.001) in the evaluation by the patients and experts with the patients' assessment being worse compared to experts' assessment. CONCLUSION: Our study showed that two years after implant-based breast reconstruction with support of TiLOOP® Bra PRO is influenced by different factors. This information can be used to improve the decision-making process for women who chose implant-based breast reconstruction.
- Zeitschriftentitel:
- Eur J Surg Oncol
- Jahr:
- 2020
- Band / Volume:
- 46
- Heft / Issue:
- 8
- Seitenangaben Beitrag:
- 1484-1490
- Volltext / DOI:
- doi:10.1016/j.ejso.2020.04.009
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/32336622
- Print-ISSN:
- 0748-7983
- TUM Einrichtung:
- Frauenklinik und Poliklinik
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