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Title:

Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis.

Document type:
Article; Book Chapter; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Damle-Vartak, Amruta; Begher-Tibbe, Brigitte; Gunther, Georgia; Geisler, Fabian; Vartak, Nachiket; Hengstler, Jan G
Abstract:
Cholestasis, the impairment of bile flux out of the liver, is a common complication of many pathological liver disorders, such as cholangiopathies, primary biliary sclerosis, and primary biliary cirrhosis. Besides accumulation of bile acids in the liver and blood, it leads to a proliferative response of the biliary tree termed as a ductular reaction. The ductular reaction is characterized by enhanced proliferation of cholangiocytes, which form the epithelial lining of bile ducts. This strong rea...     »
Journal title abbreviation:
Methods Mol Biol
Year:
2019
Journal volume:
1981
Pages contribution:
25-53
Fulltext / DOI:
doi:10.1007/978-1-4939-9420-5_3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31016646
Print-ISSN:
1064-3745
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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