Disentangling -cooperating tumor suppressor gene networks in cancer.

Titel:: Disentangling -cooperating tumor suppressor gene networks in cancer.
Dokumenttyp:: Journal Article; 4
Autor(en):: de la Rosa, Jorge; Weber, Julia; Rad, Roland; Bradley, Allan; Cadiñanos, Juan
Abstract:: We have recently performed a whole-body, genome-wide screen in mice using a single-copy inactivating transposon for the identification of (phosphatase and tensin homolog)-cooperating tumor suppressor genes (TSGs). We identified known and putative TSGs in multiple cancer types and validated the functional and clinical relevance of several promising candidates for human prostate cancer.
Zeitschriftentitel:: Mol Cell Oncol
Jahr:: 2017
Band / Volume:: 4
Heft / Issue:: 4
Seitenangaben Beitrag:: e1325550
Volltext / DOI:: doi:10.1080/23723556.2017.1325550
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/28868343
TUM Einrichtung:: Professur für Translationale gastroenterologische Onkologie (Prof. Rad)
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