Disentangling -cooperating tumor suppressor gene networks in cancer.

Title:: Disentangling -cooperating tumor suppressor gene networks in cancer.
Document type:: Journal Article; 4
Author(s):: de la Rosa, Jorge; Weber, Julia; Rad, Roland; Bradley, Allan; Cadiñanos, Juan
Abstract:: We have recently performed a whole-body, genome-wide screen in mice using a single-copy inactivating transposon for the identification of (phosphatase and tensin homolog)-cooperating tumor suppressor genes (TSGs). We identified known and putative TSGs in multiple cancer types and validated the functional and clinical relevance of several promising candidates for human prostate cancer.
Journal title abbreviation:: Mol Cell Oncol
Year:: 2017
Journal volume:: 4
Journal issue:: 4
Pages contribution:: e1325550
Fulltext / DOI:: doi:10.1080/23723556.2017.1325550
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/28868343
TUM Institution:: Professur für Translationale gastroenterologische Onkologie (Prof. Rad)
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