Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-20181.

Title:: Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-20181.
Document type:: Article; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):: Stecher, Melanie; Chaillon, Antoine; Stephan, Christoph; Knops, Elena; Kohmer, Niko; Lehmann, Clara; Eberle, Josef; Bogner, Johannes; Spinner, Christoph D; Eis-Hübinger, Anna Maria; Wasmuth, Jan-Christian; Schäfer, Guido; Behrens, Georg; Mehta, Sanjay R; Vehreschild, Jörg Janne; Hoenigl, Martin
Abstract:: We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation.
Journal title abbreviation:: Emerg Infect Dis
Year:: 2020
Journal volume:: 26
Journal issue:: 10
Pages contribution:: 2439-2443
Fulltext / DOI:: doi:10.3201/eid2610.191506
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/32946725
Print-ISSN:: 1080-6040
TUM Institution:: 1036; 602; II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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