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Titel:

Macrophage-Enriched lncRNA RAPIA: A Novel Therapeutic Target for Atherosclerosis.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Sun, Changbin; Fu, Yahong; Gu, Xia; Xi, Xiangwen; Peng, Xiang; Wang, Chuhan; Sun, Qi; Wang, Xueyu; Qian, Fengcui; Qin, Zhifeng; Qu, Wenbo; Piao, Minghui; Zhong, Shan; Liu, Shengliang; Zhang, Maomao; Fang, Shaohong; Tian, Jiangtian; Li, Chunquan; Maegdefessel, Lars; Tian, Jinwei; Yu, Bo
Abstract:
OBJECTIVE: Despite the current antiatherosclerotic and antithrombotic therapies, the incidence of advanced atherosclerosis-associated clinical events remains high. Whether long noncoding RNAs (lncRNAs) affect the progression of atherosclerosis and whether they are potential targets for the treatment of advanced atherosclerosis are poorly understood. Approach and Results: The progression of atherosclerotic lesions was accompanied by dynamic alterations in lncRNA expression, as revealed by RNA seq...     »
Zeitschriftentitel:
Arterioscler Thromb Vasc Biol
Jahr:
2020
Band / Volume:
40
Heft / Issue:
6
Seitenangaben Beitrag:
1464-1478
Volltext / DOI:
doi:10.1161/ATVBAHA.119.313749
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32268789
Print-ISSN:
1079-5642
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein)
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