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Titel:

Title: Cytokine release syndrome is not usually caused by secondary hemophagocytic lymphohistiocytosis in a cohort of 19 critically ill COVID-19 patients.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Lorenz, Georg; Moog, Philipp; Bachmann, Quirin; La Rosée, Paul; Schneider, Heike; Schlegl, Michaela; Spinner, Christoph; Heemann, Uwe; Schmid, Roland M; Algül, Hana; Lahmer, Tobias; Huber, Wolfgang; Schmaderer, Christoph
Abstract:
Severe COVID-19 associated respiratory failure, poses the one challenge of our days. Assessment and treatment of COVID-19 associated hyperinflammation may be key to improve outcomes. It was speculated that in subgroups of patients secondary hemophagocytic lymphohistiocytosis (sHLH) or cytokine release syndrome (CRS) with features of macrophage activation syndrome might drive severe disease trajectories. If confirmed, profound immunosuppressive therapy would be a rationale treatment approach. Ove...     »
Zeitschriftentitel:
Sci Rep
Jahr:
2020
Band / Volume:
10
Heft / Issue:
1
Volltext / DOI:
doi:10.1038/s41598-020-75260-w
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33106497
Print-ISSN:
2045-2322
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann); II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Klinische Chemie und Pathobiochemie; Lehrstuhl für Tumormetabolismus (Prof. Algül)
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