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Titel:

Novel prognostic histopathological grading system in oral squamous cell carcinoma based on tumour budding and cell nest size shows high interobserver and intraobserver concordance.

Dokumenttyp:
Evaluation Studies; Journal Article
Autor(en):
Boxberg, Melanie; Bollwein, Christine; Jöhrens, Korinna; Kuhn, Peer-Hendrik; Haller, Bernhard; Steiger, Katja; Wolff, Klaus-Dietrich; Kolk, Andreas; Jesinghaus, Moritz; Weichert, Wilko
Abstract:
AIMS: Squamous cell carcinoma of the oral cavity (OSCC) is a common tumour entity with a variable, partially highly aggressive clinical course. Recently, we proposed a novel (three-tiered) clinically useful grading scheme strongly associated with patient outcome in OSCC, consisting of a sum score of the histomorphological patterns tumour budding and cell nest size which outperforms WHO based grading algorithms currently in use. The aim of our study was to probe for interobserver and intraobserve...     »
Zeitschriftentitel:
J Clin Pathol
Jahr:
2019
Band / Volume:
72
Heft / Issue:
4
Seitenangaben Beitrag:
285-294
Sprache:
eng
Volltext / DOI:
doi:10.1136/jclinpath-2018-205454
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30530818
Print-ISSN:
0021-9746
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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