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Titel:

Immunohistochemical detection of receptor tyrosine kinases c-kit, EGF-R, and PDGF-R in colorectal adenocarcinomas.

Dokumenttyp:
Journal Article; Article
Autor(en):
Friederichs, J; von Weyhern, CW; Rosenberg, R; Doll, D; Busch, R; Lordick, F; Siewert, JR; Sarbia, M
Abstract:
PURPOSE: The selective inhibition of tyrosine kinases is a promising strategy in the treatment of several human malignancies. This study aimed to clarify expression patterns of therapeutically addressable receptor tyrosine kinases in colorectal cancer. MATERIALS AND METHODS: In this study, we used tissue arrays to analyze 263 specimen of colorectal carcinoma for the expression of the tyrosine kinases c-kit (CD117), epidermal growth factor receptor (EGF-R), and platelet-derived growth factor rece...     »
Zeitschriftentitel:
Langenbecks Arch Surg
Jahr:
2010
Band / Volume:
395
Heft / Issue:
4
Seitenangaben Beitrag:
373-9
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00423-009-0478-8
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19280218
Print-ISSN:
1435-2443
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Institut für Medizinische Statistik und Epidemiologie
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