Bone diseases: Interferon regulatory factor-8 suppresses osteoclastogenesis.
Document type:
News
Author(s):
Wagner, H
Abstract:
To date, understanding of the molecular mechanisms of bone metabolism has centered on three tumor necrosis factor family members--RANK, its ligand RANKL and its decoy receptor osteoprotegrin. This view should now be modified, however, to incorporate the role of interferon regulatory factor-8.