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Title:

Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Fischer, W; Windhager, L; Röhrer, S; Zeiller, M; Karnholz, A; Hoffmann, R; Zimmer, R; Haas, R
Abstract:
The availability of multiple bacterial genome sequences has revealed a surprising extent of variability among strains of the same species. The human gastric pathogen Helicobacter pylori is known as one of the most genetically diverse species. We have compared the genome sequence of the duodenal ulcer strain P12 and six other H. pylori genomes to elucidate the genetic repertoire and genome evolution mechanisms of this species. In agreement with previous findings, we estimate that the core genome...     »
Journal title abbreviation:
Nucleic Acids Res
Year:
2010
Journal volume:
38
Journal issue:
18
Pages contribution:
6089-101
Language:
eng
Fulltext / DOI:
doi:10.1093/nar/gkq378
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20478826
Print-ISSN:
0305-1048
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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