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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Hoffmann, D; Hutzenthaler, M; Seebach, J; Panning, M; Umgelter, A; Menzel, H; Protzer, U; Metzler, D
Title:
Norovirus GII.4 and GII.7 capsid sequences undergo positive selection in chronically infected patients.
Abstract:
Norovirus has become an important cause for infectious gastroenteritis. Particularly genotype II.4 (GII.4) has been shown to spread rapidly and causes worldwide pandemics. Emerging new strains evade population immunity and lead to high norovirus prevalence. Chronic infections have been described recently and will become more prevalent with increasing numbers of immunocompromized patients. Here, we studied norovirus evolution in three chronically infected patients, two genotypes II.4 and one II.7...     »
Journal title abbreviation:
Infect Genet Evol
Year:
2012
Journal volume:
12
Journal issue:
2
Pages contribution:
461-6
Language:
eng
Fulltext / DOI:
doi:10.1016/j.meegid.2012.01.020
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22310302
Print-ISSN:
1567-1348
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Virologie
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