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Titel:

In vivo image analysis of BoHV-4-based vector in mice.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Journal Article
Autor(en):
Franceschi, Valentina; Stellari, Fabio Franco; Mangia, Carlo; Jacca, Sarah; Lavrentiadou, Sophia; Cavirani, Sandro; Heikenwälder, Mathias; Donofrio, Gaetano
Abstract:
Due to its biological characteristics bovine herpesvirus 4 (BoHV-4) has been considered as an appropriate gene delivery vector. Its genomic clone, modified as a bacterial artificial chromosome (BAC), is better genetically manipulable and can be used as an efficient gene delivery and vaccine vector. Although a large amount of data have been accumulated in vitro on this specific aspect, the same cannot be asserted for the in vivo condition. Therefore, here we investigated the fate of a recombinant...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2014
Band / Volume:
9
Heft / Issue:
4
Seitenangaben Beitrag:
e95779
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0095779
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24752229
Print-ISSN:
1932-6203
TUM Einrichtung:
Institut für Virologie
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