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Title:

Role of the innate and adaptive immune responses in the course of multiple sclerosis.

Document type:
Review; Review
Author(s):
Hemmer, Bernhard; Kerschensteiner, Martin; Korn, Thomas
Abstract:
Multiple sclerosis is a chronic disease of the CNS that leads to substantial disability in most patients. The early phase is characterised by relapses and the later phase by progressive disability. Results from immunological, genetic, and histopathological studies and treatment trials have shown that the immune system plays a key part in the disease course. Findings from animal models and immunological studies of patients with multiple sclerosis suggest a change in the involvement of the immune...     »
Journal title abbreviation:
Lancet Neurol
Year:
2015
Journal volume:
14
Journal issue:
4
Pages contribution:
406-419
Language:
eng
Fulltext / DOI:
doi:10.1016/S1474-4422(14)70305-9
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25792099
Print-ISSN:
1474-4422
TUM Institution:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik
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