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Title:

Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Locatelli, Giuseppe; Baggiolini, Arianna; Schreiner, Bettina; Palle, Pushpalatha; Waisman, Ari; Becher, Burkhard; Buch, Thorsten
Abstract:
Oligodendrocytes are myelinating cells of the central nervous system which support functionally, structurally, and metabolically neurons. Mature oligodendrocytes are generally believed to be mere targets of destruction in the context of neuroinflammation and tissue damage, but their real degree of in vivo plasticity has become a matter of debate. We thus investigated the in vivo dynamic, actin-related response of these cells under different kinds of demyelinating stress.We used a novel mouse mod...     »
Journal title abbreviation:
J Neuroinflammation
Year:
2015
Journal volume:
12
Pages contribution:
62
Language:
eng
Fulltext / DOI:
doi:10.1186/s12974-015-0271-2
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25889302
Print-ISSN:
1742-2094
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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