User: Guest  Login
Title:

The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel

Document type:
Zeitschriftenaufsatz
Author(s):
Arends, Fabienna; Nowald, Constantin; Pflieger, Kerstin; Boettcher, Kathrin; Zahler, Stefan; Lieleg, Oliver
Abstract:
The migration of cells within a three-dimensional extracellular matrix (ECM) depends sensitively on the biochemical and biophysical properties of the matrix. An example for a biological ECM is given by reconstituted basal lamina gels purified from the Engelbreth-Holm-Swarm sarcoma of mice. Here, we compare four different commercial variants of this ECM, which have all been purified according to the same protocol. Nevertheless, in those gels, we detect strong differences in the migration behavior...     »
Keywords:
migration of cells, extracellular matrix, basal lamina gels, Engelbreth-Holm-Swarm
Dewey Decimal Classification:
610 Medizin und Gesundheit
Journal title:
PLoS ONE
Year:
2015
Journal volume:
10
Pages contribution:
e0118090
Covered by:
Web of Science
Language:
en
Fulltext / DOI:
doi:10.1371/journal.pone.0118090
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25689062
WWW:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118090
Publisher:
Public Library of Science (PLoS)
E-ISSN:
1932-6203
Status:
Verlagsversion / published
Submitted:
17.07.2014
Accepted:
05.01.2015
Date of publication:
17.02.2015
Semester:
WS 14-15
TUM Institution:
Fachgebiet für Biomechanik, MW
 BibTeX