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Title:

Understanding carbon catabolite repression in Escherichia coli using quantitative models

Document type:
Zeitschriftenaufsatz
Author(s):
A. Kremling, J. Geiselmann, D. Ropers, H. de Jong
Abstract:
Carbon catabolite repression (CCR) controls the order in which different carbon sources are metabolized. Although this system is one of the paradigms of the regulation of gene expression in bacteria, the underlying mechanisms remain controversial. CCR involves the coordination of different subsystems of the cell that are responsible for the uptake of carbon sources, their breakdown for the production of energy and precursors, and the conversion of the latter to biomass. The complexity of this in...     »
Keywords:
carbon catabolite repression; mathematical modeling; systems biology; Escherichia coli
Journal title:
ScienceDirect - Trends in Microbiology
Year:
2015
Year / month:
2015-02
Journal issue:
Vol. 23 No. 2
Language:
en
Fulltext / DOI:
doi:10.1016/j.tim.2014.11.002
WWW:
http://www.sciencedirect.com/science/article/pii/S0966842X14002388
TUM Institution:
FG für Systembiotechnologie
Ingested:
25.03.2015
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