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Title:

Racial Variations in Appetite-Related Hormones, Appetite, and Laboratory-Based Energy Intake from the E-MECHANIC Randomized Clinical Trial

Document type:
Zeitschriftenaufsatz
Author(s):
Dorling, James L.; Church, Timothy S.; Myers, Candice A.; Höchsmann, Christoph; White, Ursula A.; Hsia, Daniel S.; Martin, Corby K.; Apolzan, John W.
Abstract:
African Americans (AAs) have a higher obesity risk than Whites; however, it is unclear if appetite-related hormones and food intake are implicated. We examined differences in appetite-related hormones, appetite, and food intake between AAs (n = 53) and Whites (n = 111) with overweight or obesity. Participants were randomized into a control group or into supervised, controlled exercise groups at 8 kcal/kg of body weight/week (KKW) or 20 KKW. Participants consumed lunch and dinner at baseline and follow-up, with appetite and hormones measured before and after meals (except leptin). At baseline, AAs had lower peptide YY (PYY; p < 0.01) and a blunted elevation in PYY after lunch (p = 0.01), as well as lower ghrelin (p = 0.02) and higher leptin (p < 0.01) compared to Whites. Despite desire to eat being lower and satisfaction being higher in AAs relative to Whites (p ≤ 0.03), no racial differences in food intake were observed. Compared to Whites, leptin increased in the 8 KKW group in AAs (p = 0.01), yet no other race-by-group interactions were evident. Differences in appetite-related hormones between AAs and Whites exist; however, their influence on racial disparities in appetite, food intake, and obesity within this trial was limited.
Dewey Decimal Classification:
570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit; 790 Sport, Spiele, Unterhaltung
Journal title:
Nutrients
Year:
2019
Journal volume:
11
Journal issue:
9
Pages contribution:
2018
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.3390/nu11092018
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31466276
Publisher:
MDPI AG
E-ISSN:
2072-6643
Impact Factor:
6,706
Scimago Quartil:
Q1
Submitted:
20.06.2019
Accepted:
24.08.2019
Date of publication:
28.08.2019
Semester:
SS 19
TUM Institution:
Professur für Bewegung, Ernährung und Gesundheit
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