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Title:

Comparative analysis of bone regeneration behavior using recombinant human BMP-2 versus plasmid DNA of BMP-2.

Document type:
Journal Article
Author(s):
Kolk, Andreas; Boskov, Marko; Haidari, Selgai; Tischer, Thomas; Van Griensven, Martijn; Bissinger, Oliver; Plank, Christian
Abstract:
Bone regeneration and the osteoinductive capacity of implants are challenging issues in clinical medicine. Currently, recombinant growth factors and nonviral gene transfer are the most frequently investigated methods for bone growth enhancement, although the more favorable method remains unclear. There is a lack of knowledge in literature about the in vivo comparison of these methods for bone regeneration. BMP-2, which is the most commonly used growth factor for osteogenesis, was applied at its...     »
Journal title abbreviation:
J Biomed Mater Res A
Year:
2019
Journal volume:
107
Journal issue:
1
Pages contribution:
163-173
Fulltext / DOI:
doi:10.1002/jbm.a.36545
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30358084
Print-ISSN:
1549-3296
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Klinik und Poliklinik für Unfallchirurgie
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