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Title:

NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Wuerth, Jennifer Deborah; Habjan, Matthias; Wulle, Julia; Superti-Furga, Giulio; Pichlmair, Andreas; Weber, Friedemann
Abstract:
Sandfly fever Sicilian virus (SFSV) is one of the most widespread and frequently identified members of the genus Phlebovirus (order Bunyavirales, family Phenuiviridae) infecting humans. Being transmitted by Phlebotomus sandflies, SFSV causes a self-limiting, acute, often incapacitating febrile disease ("sandfly fever," "Pappataci fever," or "dog disease") that has been known since at least the beginning of the 20th century. We show that, similarly to other pathogenic phleboviruses, SFSV suppress...     »
Journal title abbreviation:
J Virol
Year:
2018
Journal volume:
92
Journal issue:
23
Fulltext / DOI:
doi:10.1128/JVI.01202-18
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30232186
Print-ISSN:
0022-538X
TUM Institution:
Institut für Virologie
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