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Titel:

Transparent Nanopore Cavity Arrays Enable Highly Parallelized Optical Studies of Single Membrane Proteins on Chip

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Diederichs, T.; Nguyen. Q. H.; Urban, M.; Tampé, R.; Tornow, M.
Abstract:
Membrane proteins involved in transport processes are key targets for pharmaceutical research and industry. Despite continuous improvements and new developments in the field of electrical readouts for the analysis of transport kinetics, a well-suited methodology for high-throughput characterization of single transporters with nonionic substrates and slow turnover rates is still lacking. Here, we report on a novel architecture of silicon chips with embedded nanopore microcavities, based on a sili...     »
Stichworte:
Vesicles,Layers,Silicon,Cavities,Nanopores
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
Nano Lett. 18, 6, 3901–3910 2018-05
Jahr:
2018
Jahr / Monat:
2018-05
Quartal:
2. Quartal
Monat:
May
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1021/acs.nanolett.8b01252
WWW:
https://pubs.acs.org/doi/10.1021/acs.nanolett.8b01252
Verlag / Institution:
American Chemical Society ACS
TUM Einrichtung:
Professur für Molekularelektronik
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