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Titel:

Novel cysteine- and albumin-adduct biomarkers to prove human poisoning with the pesticide oxydemeton-S-methyl.

Dokumenttyp:
Case Reports; Journal Article
Autor(en):
John, Harald; Siegert, Markus; Eyer, Florian; Worek, Franz; Thiermann, Horst; Kranawetvogl, Andreas
Abstract:
We herein report on the forensic analysis of plasma samples to prove human poisoning with oxydemeton-S-methyl (ODM), S-(2-(ethylsulfinyl)ethyl)-O,O-dimethyl phosphorothioate. This organophosphorus pesticide is the active ingredient of Metasystox, that was swallowed by a 77-year-old woman to commit suicide. ODM belongs to the class of dimethyl phosphoryl (DMP) pesticides, contains a 2-(ethylsulfinyl)ethanethiol (ESOET) leaving group and undergoes adduct formation with endogenous molecules as elab...     »
Zeitschriftentitel:
Toxicol Lett
Jahr:
2018
Band / Volume:
294
Seitenangaben Beitrag:
122-134
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.toxlet.2018.05.023
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29777832
Print-ISSN:
0378-4274
TUM Einrichtung:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker)
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