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Title:

Cannabinoid Receptor Type 1 in the Brain Regulates the Affective Component of Visceral Pain in Mice.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bajic, Danica; Monory, Krisztina; Conrad, Andrea; Maul, Christina; Schmid, Roland M; Wotjak, Carsten T; Stein-Thoeringer, Christoph K
Abstract:
Endocannabinoids acting through cannabinoid receptor type 1 (CB1) are major modulators of peripheral somatic and visceral nociception. Although only partially studied, some evidence suggests a particular role of CB1 within the brain in nociceptive processes. As the endocannabinoid system regulates affect and emotional behaviors, we hypothesized that cerebral CB1 influences affective processing of visceral pain-related behaviors in laboratory animals. To study nocifensive responses modulated by s...     »
Journal title abbreviation:
Neuroscience
Year:
2018
Journal volume:
384
Pages contribution:
397-405
Fulltext / DOI:
doi:10.1016/j.neuroscience.2018.05.041
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29885522
Print-ISSN:
0306-4522
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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