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- Original title:
- Identification and characterization of vacuolar fusion defective (vfd) mutants in Arabidopsis thaliana
- Translated title:
- Identifizierung und Charakterisierung von vacuolar fusion defective (vfd) Mutanten in Arabidopsis thaliana
- Author:
- Kolb, Cornelia
- Year:
- 2017
- Document type:
- Dissertation
- Faculty/School:
- Fakultät Wissenschaftszentrum Weihenstephan
- Advisor:
- Schwechheimer, Claus (Prof. Dr.)
- Referee:
- Schwechheimer, Claus (Prof. Dr.); Hückelhoven, Ralph (Prof. Dr.)
- Language:
- en
- Subject group:
- BIO Biowissenschaften
- Keywords:
- AMSH3, Arabidopsis, EMS, endocytosis, forward genetics, FYVE, mutant screen, vacuole biogenesis, PI3P
- Translated keywords:
- AMSH3, Arabidopsis, EMS, Endozytose, FYVE, Mutanten-Screen, PI3P, Vakuolenbiogenese, Vorwärtsgenetik
- TUM classification:
- BIO 400d
- Abstract:
- The plant vacuole is a central organelle that is involved in various biological processes. The vacuolar fusion defective (vfd) mutants show seedling lethality and defects in central vacuole formation. VFD1 encodes a Fab1, YOTB, Vac1, and EEA1 (FYVE) domain-containing protein, FYVE1, that has been implicated in intracellular trafficking. This study shows that FYVE1 is essential for plant growth and development and place FYVE1 as a key regulator of intracellular trafficking and vacuole biogenesis.
- Translated abstract:
- Die Pflanzenvakuole ist ein zentrales Organell, das in diverse biologische Prozesse involviert ist. Die vacuolar fusion defective (vfd) Mutanten zeigen Keimlingsletalität und Defekte in der Bildung der Zentralvakuole. VFD1 kodiert für das Fab1, YOTB, Vac1 und EEA1 (FYVE) Domäne enthaltende Protein FYVE1, das in Zusammenhang mit intrazellulärem Transport steht. Diese Studie zeigt, dass FYVE1 essentiell für Pflanzenwachstum und Entwicklung ist und stuft FYVE1 als Schlüsselregulator des intrazellul... »
- WWW:
- https://mediatum.ub.tum.de/?id=1350677
- Date of submission:
- 13.03.2017
- Oral examination:
- 11.07.2017
- File size:
- 11853556 bytes
- Pages:
- 115
- Urn (citeable URL):
- https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20170711-1350677-1-0
- Last change:
- 26.09.2017
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