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Document type:
Konferenzbeitrag 
Author(s):
Mohamed A, Sun C, De Mello V, Pobbati BA, Tremblay A, Schoenfelder M, Missiaglia E, Vargesson N, Hong W, Zammit P, Wackerhage H 
Title:
Vgll3 is up-regulated during muscle regeneration, regulates muscle differentiation ex vivo and is highly expressed in human alveolar rhabdomyosarcoma (ARMS) 
Pages contribution:
65 
Abstract:
Vgll1-4 (also known as Vito’s) bind Tead1-4 transcription factors through their Tondu domain at the same site where Yap binds (Pobbati et al., 2012). Intriguingly the expression of the ARMS fusion gene PAX3-FOXO1 increases Vgll3 expression 8.41-fold in the developing chick limb (Lagha et al., 2010). Consistent with this, Vgll3 expression is highest in PAX3-FOXO1-positive ARMS when compared to other types of rhabdomyosarcoma and differentiated skeletal muscle. Vgll3 expression increases more tha...    »
 
Dewey Decimal Classification:
570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit 
Book / Congress title:
The Hippo pathway across species and disciples 
Date of congress:
25-29 Oct 2017 
Year:
2017 
Language:
en 
Semester:
WS 17-18 
TUM Institution:
Sportbiologie