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Titel:

Chromium(VI) Contact Dermatitis: Getting Closer to Understanding the Underlying Mechanisms of Toxicity and Sensitization!

Dokumenttyp:
Journal Article; Editorial Material
Autor(en):
Buters, Jeroen; Biedermann, Tilo
Abstract:
Various haptens trigger innate immune pathways and/or induce cytotoxicity as a part of sensitization. Adam et al. decipher in vitro the mechanisms by which chromium(VI) induces inflammation, the likely prerequisites for toxicity, sensitization, and allergic contact dermatitis against chromium(VI). Importantly, and in line with other observations, chromium(VI), but not chromium(III) (or Ni(II)), induces mitochondrial reactive oxygen species accumulation. Mitochondrial reactive oxygen species in t...     »
Zeitschriftentitel:
J Invest Dermatol
Jahr:
2017
Band / Volume:
137
Heft / Issue:
2
Seitenangaben Beitrag:
274-277
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jid.2016.11.015
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28110709
Print-ISSN:
0022-202X
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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