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Title:

D-tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease.

Document type:
Journal Article
Author(s):
Kepert, Inge; Fonseca, Juliano; Müller, Constanze; Milger, Katrin; Hochwind, Kerstin; Kostric, Matea; Fedoseeva, Maria; Ohnmacht, Caspar; Dehmel, Stefan; Nathan, Petra; Bartel, Sabine; Eickelberg, Oliver; Schloter, Michael; Hartmann, Anton; Schmitt-Kopplin, Philippe; Krauss-Etschmann, Susanne
Abstract:
Chronic immune diseases, such as asthma, are highly prevalent. Currently available pharmaceuticals improve symptoms but cannot cure the disease. This prompted demands for alternatives to pharmaceuticals, such as probiotics, for the prevention of allergic disease. However, clinical trials have produced inconsistent results. This is at least partly explained by the highly complex crosstalk among probiotic bacteria, the host's microbiota, and immune cells. The identification of a bioactive substanc...     »
Journal title abbreviation:
J Allergy Clin Immunol
Year:
2017
Journal volume:
139
Journal issue:
5
Pages contribution:
1525-1535
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jaci.2016.09.003
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27670239
Print-ISSN:
0091-6749
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
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