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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Burbage, Marianne; Keppler, Selina J; Montaner, Beatriz; Mattila, Pieta K; Batista, Facundo D 
Title:
The Small Rho GTPase TC10 Modulates B Cell Immune Responses. 
Abstract:
Rho family GTPases regulate diverse cellular events, such as cell motility, polarity, and vesicle traffic. Although a wealth of data exists on the canonical Rho GTPases RhoA, Rac1, and Cdc42, several other family members remain poorly studied. In B cells, we recently demonstrated a critical role for Cdc42 in plasma cell differentiation. In this study, we focus on a close homolog of Cdc42, TC10 (also known as RhoQ), and investigate its physiological role in B cells. By generating a TC10-deficient...    »
 
Journal title abbreviation:
J Immunol 
Year:
2017 
Journal volume:
199 
Journal issue:
Pages contribution:
1682-1695 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0022-1767 
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie