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Title:

Increased choline uptake in macrophages and prostate cancer cells does not allow for differentiation between benign and malignant prostate pathologies.

Document type:
Journal Article
Author(s):
Schwarz, Timo; Seidl, Christof; Schiemann, Matthias; Senekowitsch-Schmidtke, Reingard; Krause, Bernd Joachim
Abstract:
Inflammatory cells may contribute to the choline uptake in different prostate pathologies. The aim of this study was (i) to assess if inflammatory cells incorporate choline and (ii) to potentially detect differences compared to FDG uptake. Therefore we investigated the uptake of [(3)H]choline and [(18)F]FDG in human prostate carcinoma cells and human inflammatory cells.Macrophages were cultured from isolated mononuclear cells, gained by density gradient centrifugation of human buffy coats. T-lym...     »
Journal title abbreviation:
Nucl Med Biol
Year:
2016
Journal volume:
43
Journal issue:
6
Pages contribution:
355-9
Language:
eng
Fulltext / DOI:
doi:10.1016/j.nucmedbio.2016.02.004
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27260776
Print-ISSN:
0969-8051
TUM Institution:
Frauenklinik und Poliklinik; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Klinik und Poliklinik für Nuklearmedizin
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