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Titel:

TIL 2.0: More effective and predictive T-cell products by enrichment for defined antigen specificities.

Dokumenttyp:
Journal Article
Autor(en):
Schober, Kilian; Busch, Dirk H
Abstract:
Adoptive transfer of in vitro-expanded T cells derived from tumor-infiltrating lymphocytes (TILs) in melanoma patients started the era of tumor immunotherapy three decades ago. The approach has demonstrated remarkable clinical responses in several studies since. Reinfusion of TIL-derived T cells represents a highly personalized form of immunotherapy, taking into account the enormous interindividual tumor heterogeneity. However, despite its successes, TIL therapy does not lead to objective clinic...     »
Zeitschriftentitel:
Eur J Immunol
Jahr:
2016
Band / Volume:
46
Heft / Issue:
6
Seitenangaben Beitrag:
1335-9
Sprache:
eng
Volltext / DOI:
doi:10.1002/eji.201646436
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27280482
Print-ISSN:
0014-2980
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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