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Title:

Corticothalamic Spike Transfer via the L5B-POm Pathway in vivo.

Document type:
Journal Article; Article
Author(s):
Mease, Rebecca A; Sumser, Anton; Sakmann, Bert; Groh, Alexander
Abstract:
The cortex connects to the thalamus via extensive corticothalamic (CT) pathways, but their function in vivo is not well understood. We investigated "top-down" signaling from cortex to thalamus via the cortical layer 5B (L5B) to posterior medial nucleus (POm) pathway in the whisker system of the anesthetized mouse. While L5B CT inputs to POm are extremely strong in vitro, ongoing activity of L5 neurons in vivo might tonically depress these inputs and thereby block CT spike transfer. We find robus...     »
Journal title abbreviation:
Cereb Cortex
Year:
2016
Journal volume:
26
Journal issue:
8
Pages contribution:
3461-75
Language:
eng
Fulltext / DOI:
doi:10.1093/cercor/bhw123
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27178196
Print-ISSN:
1047-3211
TUM Institution:
Institut für Neurowissenschaften; Neurochirurgische Klinik und Poliklinik
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