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Titel:

Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Kriebel, Jennifer; Herder, Christian; Rathmann, Wolfgang; Wahl, Simone; Kunze, Sonja; Molnos, Sophie; Volkova, Nadezda; Schramm, Katharina; Carstensen-Kirberg, Maren; Waldenberger, Melanie; Gieger, Christian; Peters, Annette; Illig, Thomas; Prokisch, Holger; Roden, Michael; Grallert, Harald
Abstract:
Epigenetic regulation has been postulated to affect glucose metabolism, insulin sensitivity and the risk of type 2 diabetes. Therefore, we performed an epigenome-wide association study for measures of glucose metabolism in whole blood samples of the population-based Cooperative Health Research in the Region of Augsburg F4 study using the Illumina HumanMethylation 450 BeadChip. We identified a total of 31 CpG sites where methylation level was associated with measures of glucose metabolism after a...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2016
Band / Volume:
11
Heft / Issue:
3
Seitenangaben Beitrag:
e0152314
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0152314
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27019061
Print-ISSN:
1932-6203
TUM Einrichtung:
Institut für Humangenetik
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