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Title:

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations.

Document type:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Lamina, Claudia; Friedel, Salome; Coassin, Stefan; Rueedi, Rico; Yousri, Noha A; Seppälä, Ilkka; Gieger, Christian; Schönherr, Sebastian; Forer, Lukas; Erhart, Gertraud; Kollerits, Barbara; Marques-Vidal, Pedro; Ried, Janina; Waeber, Gerard; Bergmann, Sven; Dähnhardt, Doreen; Stöckl, Andrea; Kiechl, Stefan; Raitakari, Olli T; Kähönen, Mika; Willeit, Johann; Kedenko, Ludmilla; Paulweber, Bernhard; Peters, Annette; Meitinger, Thomas; Strauch, Konstantin; Lehtimäki, Terho; Hunt, Steven C; Vollenwei...     »
Abstract:
Apolipoprotein A-IV (apoA-IV) is a major component of HDL and chylomicron particles and is involved in reverse cholesterol transport. It is an early marker of impaired renal function. We aimed to identify genetic loci associated with apoA-IV concentrations and to investigate relationships with known susceptibility loci for kidney function and lipids. A genome-wide association meta-analysis on apoA-IV concentrations was conducted in five population-based cohorts (n = 13,813) followed by two addit...     »
Journal title abbreviation:
Hum Mol Genet
Year:
2016
Journal volume:
25
Journal issue:
16
Pages contribution:
3635-3646
Language:
eng
Fulltext / DOI:
doi:10.1093/hmg/ddw211
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27412012
Print-ISSN:
0964-6906
TUM Institution:
Institut für Humangenetik
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