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Titel:

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Dokumenttyp:
Journal Article; Meta-Analysis
Autor(en):
Graff, Mariaelisa; Scott, Robert A; Justice, Anne E; Young, Kristin L; Feitosa, Mary F; Barata, Llilda; Winkler, Thomas W; Chu, Audrey Y; Mahajan, Anubha; Hadley, David; Xue, Luting; Workalemahu, Tsegaselassie; Heard-Costa, Nancy L; den Hoed, Marcel; Ahluwalia, Tarunveer S; Qi, Qibin; Ngwa, Julius S; Renström, Frida; Quaye, Lydia; Eicher, John D; Hayes, James E; Cornelis, Marilyn; Kutalik, Zoltan; Lim, Elise; Luan, Jian'an; Huffman, Jennifer E; Zhang, Weihua; Zhao, Wei; Griffin, Paula J; Haller,...     »
Abstract:
Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumference and waist-hip ratio from up to 200,452 adults of European (n = 180,423) or other ancestry (n = 20,029). We standardized PA by categorizing it into a dichotomous variable where, on average, 23% of participants were categorized as inactive and 77%...     »
Zeitschriftentitel:
PLoS Genet
Jahr:
2017
Band / Volume:
13
Heft / Issue:
4
Seitenangaben Beitrag:
e1006528
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pgen.1006528
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28448500
Print-ISSN:
1553-7390
TUM Einrichtung:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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