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Titel:

ProteomeTools: Systematic Characterization of 21 Post-translational Protein Modifications by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Using Synthetic Peptides

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Zolg, Daniel Paul; Wilhelm, Mathias; Schmidt, Tobias; Médard, Guillaume; Zerweck, Johannes; Knaute, Tobias; Wenschuh, Holger; Reimer, Ulf; Schnatbaum, Karsten; Kuster, Bernhard
Abstract:
The analysis of the post-translational modification (PTM) state of proteins using mass spectrometry-based bottom-up proteomic workflows has evolved into a powerful tool for the study of cellular regulatory events that are not directly encoded at the genome level. Besides frequently detected modifications such as phosphorylation, acetylation and ubiquitination, many low abundant or less frequently detected PTMs are known or postulated to serve important regulatory functions. To more broadly under...     »
Zeitschriftentitel:
Molecular & Cellular Proteomics
Jahr:
2018
Band / Volume:
17
Heft / Issue:
9
Seitenangaben Beitrag:
1850-1863
Volltext / DOI:
doi:10.1074/mcp.tir118.000783
Verlag / Institution:
American Society for Biochemistry & Molecular Biology (ASBMB)
E-ISSN:
1535-94761535-9484
Publikationsdatum:
29.05.2018
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