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Titel:

T cell responses in the central nervous system.

Dokumenttyp:
Journal Article; Review
Autor(en):
Korn, Thomas; Kallies, Axel
Abstract:
T cells are required for immune surveillance of the central nervous system (CNS); however, they can also induce severe immunopathology in the context of both viral infections and autoimmunity. The mechanisms that are involved in the priming and recruitment of T cells to the CNS are only partially understood, but there has been renewed interest in this topic since the 'rediscovery' of lymphatic drainage from the CNS. Moreover, tissue-resident memory T cells have been detected in the CNS and are...     »
Zeitschriftentitel:
Nat Rev Immunol
Jahr:
2017
Band / Volume:
17
Heft / Issue:
3
Seitenangaben Beitrag:
179-194
Sprache:
eng
Volltext / DOI:
doi:10.1038/nri.2016.144
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28138136
Print-ISSN:
1474-1733
TUM Einrichtung:
Molekulare Immunologie (Prof. Knolle)
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