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Titel:

Do selective radiation dose escalation and tumour hypoxia status impact the loco-regional tumour control after radio-chemotherapy of head & neck tumours? The ESCALOX protocol.

Dokumenttyp:
Journal Article; Article
Autor(en):
Pigorsch, Steffi U; Wilkens, Jan J; Kampfer, Severin; Kehl, Victoria; Hapfelmeier, Alexander; Schläger, Christian; Bier, Henning; Schwaiger, Markus; Combs, Stephanie E
Abstract:
Standard of care primary treatment of carcinoma of locally advanced squamous cell head and neck cancer (LAHNSCC) consists of platinum-based concomitant chemo-irradiation. Despite progress in the treatment of LAHNSCC using modern radiotherapy techniques the outcome remains still poor. Using IMRT with SIB the escalation of total dose to the GTV is possible with the aim to improve clinical outcome. This study tests the hypothesis if radiation dose escalation to the GTV improves 2-year-LRC and -OS a...     »
Zeitschriftentitel:
Radiat Oncol
Jahr:
2017
Band / Volume:
12
Heft / Issue:
1
Seitenangaben Beitrag:
45
Sprache:
eng
Volltext / DOI:
doi:10.1186/s13014-017-0776-1
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28249612
Print-ISSN:
1748-717X
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Kliniken und Institute
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